Magali Moretto
Faculty Member
Over the years I have gained proficiency in performing polychromatic flow cytometry (up to 14 colors), generating bone marrow chimeric mice and performing crosses in transgenic animals. I have studied immune response against several gut pathogens like Toxoplasma gondii, Cryptosporidium parvum and Encephalitozoon cuniculi, which has led to more than 25 publications in well-reputed journals.
My current research interests are to study CD4 and CD8 memory T cells as well as CD8 tissue resident memory T cells in the brain of toxoplasma infected mice and their importance in protection against the infection. For this purpose, I have been using Toxoplasma gondii, a parasite that infects a wide range of hosts including humans. Also, I recently started working on CD8 disfunction and the mechanism leading to the loss of function and parasite reactivation. Both of these projects have or will shortly yield publications and grant submission.
I will also include epigenetic studies in collaboration with Dr Kate Chiappinelli (Single cell RNA sequencing, ATAC sequencing) in the very near future.
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Background
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