My research involves the design, synthesis and evaluation of small molecules as effective antimicrobial agents. Our work has focused on finding new drugs against tuberculosis and malaria. We have contributed many papers on this topic and received significant external funding. This year (2021) saw a continuation of our work in these areas, due to maintenance of productive collaborations with Drs. Audrey Odom John (Children's Hospital of Philadelphia), Robin Couch (GMU), Marvin Meyers (St. Louis University), and Helena Boshoff (NIH). This multi-institution collaboration around Dxr continues to be well-supported from NIH. In addition, I have continued our international collaboration with Dr. Erick Strauss (Stellenbosch University, South Africa) on a project around CoaBC enzymes. This project with Dr. Strauss continues to receive significant funding from NIH. I look forward to continued and further success with these investigators. Newer collaborators include Drs. Sherry Mowbray (University of Uppsala, Sweden), Paul Hruz (Washington University), John Hawdon (GWU), and Ling Hao (GWU).
This year, in addition to research and teaching, I have continued to spend considerable time in service to the Chemistry Department and CCAS. In the Department, I continue to serve as the Chair of Graduate Admissions and Recruitment as well as serve on the Department’s Personnel and Graduate Curriculum committees. I continued service to CCAS on the CCAS Dean’s Council (through May 2021). In addition, I was asked by the Dean to serve on an ad hoc CCAS Budget advisory committee. At the University level, I was elected to represent CCAS on the Faculty Consultative Committee as part of the search for our next president. I served on a Forensics Science search committee as well as a search committee for a Teaching Assistant Professor in Chemistry. Outside GW, I continued serving as a permanent member of the NIH's DDR study section (ended July 2021). I regularly review grants for NIH, as well as journal articles for a variety of scientific publications.